EPISODE # 8

Insights Into Over & Under Methylation with Scientist James Bradshaw

Symptoms of Over & Under Methylation Are Very Similar

In this episode of the Histamine Well, Joanne is joined by scientist James Bradshaw to discuss the complexities of methylation and its critical role in genetics, mood, and overall health. 

James shares his extensive background in biochemistry and cellular biology and introduces Mood Sense, the first saliva test for assessing methylation-related mood disruptions. 

They explore the essentials of methylation, its impact on neurotransmitter production, and the difference between over and under methylation. 

The episode also delves into genetic mutations, environmental factors affecting methylation, and practical approaches to managing methylation in clinical practice. 

Listeners gain insights into the role of methylation in various chronic health conditions and how personalized testing can lead to better health outcomes.

Today we discuss:

  • Understanding Methylation
  • Genetic and Environmental Impacts on Methylation
  • Over Methylation: Symptoms and Causes
  • Under Methylation: Symptoms and Causes
  • Adverse Reactions to Exercise
  • Impact of Folic Acid on Methylation
  • Aluminum and Methylation Disruption
  • B12 and Methylation Pathways
  • BHMT Gene and Alternative Pathways
  • Niacinamide and Vitamin C for Over Methylation
  • Homocysteine Levels and Methylation
  • Methylation Testing and Clinical Applications

“ I remember the first time that I balanced my methylation. I had this feeling of euphoria that said, is this how normal people feel? ’cause I, I hadn’t, I hadn’t felt that my entire life.”

James Bradshaw

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